What is vulvovaginal atrophy (VVA)?

A depletion of endogenous estrogens occurs postmenopausally as a result of a decline in ovarian function, and may cause symptomatic VVA.1

Vaginal atrophy becomes clinically apparent 4–5 years after menopause.2

Physical signs of VVA include:

  • Diminished vaginal rugae2
  • Reduced blood flow leading to a pale appearance2
  • Change in vaginal pH from the moderately acidic range (pH 3.5–5.0) to a neutral range (pH 6.0–8.0)2
  • Shift in the vaginal maturation index2