What is vulvovaginal atrophy (VVA)?
A depletion of endogenous estrogens occurs postmenopausally as a result of a decline in ovarian function, and may cause symptomatic VVA.1
Vaginal atrophy becomes clinically apparent 4–5 years after menopause.2
Physical signs of VVA include:
- Diminished vaginal rugae2
- Reduced blood flow leading to a pale appearance2
- Change in vaginal pH from the moderately acidic range (pH 3.5–5.0) to a neutral range (pH 6.0–8.0)2
- Shift in the vaginal maturation index2